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Научно-практическая ревматология

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ИНТЕРЛЕЙКИН 1 КАК МЕДИАТОР ВОСПАЛЕНИЯ И ТЕРАПЕВТИЧЕСКАЯ МИШЕНЬ

https://doi.org/10.14412/1995-4484-2011-1463

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Аннотация

Интерлейкин 1 (ИЛ 1) впервые был описан в 40-х го- дах XX в. как вызывающий лихорадку фактор, высвобож- даемый активированными лейкоцитами. В то время он на- зывался «пирексин» или «эндогенный пироген» [1]. Как правило, клетки организма не способны к спонтанному синтезу ИЛ 1, а отвечают его продукцией на инфекцию, действие микробных токсинов, воспалительных агентов, других цитокинов, активированных компонентов компле- мента или системы свертывания крови [2, 3].

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Для цитирования:


Ильина А.Е., Станислав М.Л., Денисов Л.Н., Насонов Е.Л. ИНТЕРЛЕЙКИН 1 КАК МЕДИАТОР ВОСПАЛЕНИЯ И ТЕРАПЕВТИЧЕСКАЯ МИШЕНЬ. Научно-практическая ревматология. 2011;49(5):62-71. https://doi.org/10.14412/1995-4484-2011-1463

For citation:


Il'ina A.E., Stanislav M.L., Denisov L.N., Nasonov E.L. INTERLEIKIN 1 KAK MEDIATOR VOSPALENIYa I TERAPEVTIChESKAYa MIShEN''. Rheumatology Science and Practice. 2011;49(5):62-71. (In Russ.) https://doi.org/10.14412/1995-4484-2011-1463

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