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Научно-практическая ревматология

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ПОРАЖЕНИЕ КИШЕЧНИКА У БОЛЬНЫХ СПОНДИЛОАРТРИТАМИ

https://doi.org/10.14412/1995-4484-2015-190-199

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Аннотация

Патогенетическая и клиническая ассоциация между спондилоартритами (СпА) и воспалительными заболеваниями  кишечника (ВЗК) хорошо известна. Язвенный  колит и болезнь Крона значительно чаще встречаются у больных СпА, чем в популяции. В свою очередь, поражение  позвоночника и периферических суставов является  типичным системным  проявлением ВЗК. Но при этом не менее половины  больных СпА имеют эндоскопические и гистологические признаки хронического  воспаления слизистой оболочки тонкой и толстой кишки, которые не сопровождаются отчетливо выраженными клиническими проявлениями и не могут рассматриваться в рамках конкретной нозологической формы. Значение этой патологии  до настоящего  времени неясно.  Следует ли рассматривать бессимптомное кишечное  воспаление  как предвестник развития «настоящих» ВЗК, какие методы следует использовать  для диагностики поражения кишечника и как наличие этой патологии  влияет на выбор рациональной фармакотерапии СпА? В настоящем обзоре представлен анализ основных  данных литературы,  касающихся этой проблемы.

Об авторах

А. Е. Каратеев
Научноисследовательский институт ревматологии им В.А. Насоновой, Москва
Россия

Контакты: Андрей Евгеньевич Каратеев; aekarateev@rambler.ru



Е. А. Галушко
Научноисследовательский институт ревматологии им В.А. Насоновой, Москва
Россия


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Для цитирования:


Каратеев А.Е., Галушко Е.А. ПОРАЖЕНИЕ КИШЕЧНИКА У БОЛЬНЫХ СПОНДИЛОАРТРИТАМИ. Научно-практическая ревматология. 2015;53(2):190-199. https://doi.org/10.14412/1995-4484-2015-190-199

For citation:


Karateev A.E., Galushko E.A. BOWEL INVOLVEMENT IN PATIENTS WITH SPONDYLOARTHRITIS. Rheumatology Science and Practice. 2015;53(2):190-199. (In Russ.) https://doi.org/10.14412/1995-4484-2015-190-199

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)