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Научно-практическая ревматология

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Иммуновоспалительные ревматические заболевания, связанные с интерфероном типа I: новые данные

https://doi.org/10.14412/1995-4484-2019-452-461

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Аннотация

Иммуновоспалительные ревматические заболевания (ИВРЗ) – большая группа патологических состояний, в основе которых лежит нарушение иммунологической толерантности к собственным тканям, ведущее к воспалению и необратимым органным повреждениям. В обзоре рассмотрены современные представления о роли интерферонов типа I в иммунопатогенезе ИВРЗ, в первую очередь системной красной волчанки, и новые возможности персонифицированной терапии.

Об авторах

Е. Л. Насонов
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой», ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)
Россия

научный руководитель ФГБНУ «НИИР им. В.А. Насоновой», академик РАН, профессор, докт. мед. наук

115522, Москва, Каширское шоссе, 34А
119991, Москва, ул. Трубецкая, 8, стр. 2



А. С. Авдеева
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия

научный сотрудник лаборатории стандартизации терапии ревматических заболеваний, канд. мед. наук

115522, Москва, Каширское шоссе, 34А



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Для цитирования:


Насонов Е.Л., Авдеева А.С. Иммуновоспалительные ревматические заболевания, связанные с интерфероном типа I: новые данные. Научно-практическая ревматология. 2019;57(4):452-461. https://doi.org/10.14412/1995-4484-2019-452-461

For citation:


Nasonov E.L., Avdeeva A.S. IMMUNOINFLAMMATORY RHEUMATIC DISEASES ASSOCIATED WITH TYPE I INTERFERON: NEW EVIDENCE. Rheumatology Science and Practice. 2019;57(4):452-461. (In Russ.) https://doi.org/10.14412/1995-4484-2019-452-461

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)