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Научно-практическая ревматология

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По материалам обновленных рекомендаций Европейской антиревматической лиги (EULAR) по лечению системной красной волчанки – 2019: дискуссионные вопросы и комментарии

https://doi.org/10.14412/1995-4484-2019-496-510

Полный текст:

Аннотация

Многообразие клинических проявлений системной красной  волчанки  (СКВ),  волнообразное течение с чередованием ремиссий  и обострений  делают это заболевание одним из наиболее трудных для диагностики, лечения и оценки  эффективности терапии.

Несмотря  на то что разработанные в последние  годы методы ранней диагностики, способы применения комбинированной патогенетической терапии и мониторинга течения болезни привели  к увеличению  выживаемости (≥90%) и продолжительности жизни пациентов с СКВ, остается еще много нерешенных проблем. В частности, эффективность лечения СКВ пока не достаточна и полностью  контролировать активность  заболевания удается нечасто. Рецидивирующее течение СКВ в сочетании  с коморбидной патологией, а также неблагоприятным воздействием  глюкокортикоидов (ГК) и иммуносупрессантов способствует накоплению необратимых  органных повреждений.

Статья посвящена обзору обновленных рекомендаций Европейской антиревматической лиги (EULAR)  по лечению СКВ, которые были опубликованы в 2019 г. Представлены комментарии и дискуссионные вопросы с учетом российских  рекомендаций по лечению СКВ.

Об авторах

Т. В. Попкова
Научно-исследовательский институт ревматологии им. В.А. Насоновой
Россия

Попкова Татьяна Валентиновна.

115522, Москва, Каширское шоссе, 34А.



Т. А. Панафидина
Научно-исследовательский институт ревматологии им. В.А. Насоновой
Россия

115522, Москва, Каширское шоссе, 34А.



С. К. Соловьев
Научно-исследовательский институт ревматологии им. В.А. Насоновой
Россия

115522, Москва, Каширское шоссе, 34А.



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Для цитирования:


Попкова Т.В., Панафидина Т.А., Соловьев С.К. По материалам обновленных рекомендаций Европейской антиревматической лиги (EULAR) по лечению системной красной волчанки – 2019: дискуссионные вопросы и комментарии. Научно-практическая ревматология. 2019;57(5):496-510. https://doi.org/10.14412/1995-4484-2019-496-510

For citation:


Popkova T.V., Panafidina T.A., Solovyev S.K. According to the 2019 updated European League Against Rheumatism (EULAR) recommendations for the treatment of systemic lupus erythematosus: debatable issues and comments. Rheumatology Science and Practice. 2019;57(5):496-510. (In Russ.) https://doi.org/10.14412/1995-4484-2019-496-510

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ISSN 1995-4484 (Print)
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